CHARACTERIZATION, RECOMBINANT PRODUCTION AND STRUCTURE-FUNCTION ANALYSIS OF NVCI, A PICOMOLAR METALLOCARBOXYPEPTIDASE INHIBITOR FROM THE MARINE SNAIL NERITA VERSICOLOR

A very powerful proteinaceous inhibitor of metallocarboxypeptidases has been isolated from the marine snail Nerita versicolor and characterized in depth.The most abundant of four, very similar isoforms, NvCla, was taken as reference and N-terminally sequenced to obtain a 372-nucleotide band coding for the protein cDNA.The mature protein contains 53

Towards tackling the phenomenon of textual information overload that is exponentially pumping with redundancy over the Internet, this paper investigates a solution depending on the Automatic Text Summarization (ATS) method.The idea of ATS Face Exfoliant is to assist, e.g., online readers, in getting a simplified version of texts for preserving thei

Efficacy of mesenchymal stem cells (MSCs) for treatment of acute respiratory distress syndrome (ARDS) suggests bioactive bone marrow MSC extracellular vesicles (BM-MSC EVs) may be effective.A patient with severe COVID-19 associated ARDS who was presumed to expire was treated with a BM-MSC EV preparation (14 doses over two months) as Numeric Keyboar

In this paper, the nonlinear mechanical response of elastic cable structures under mechanical load is studied based on the discrete catenary theory.A cable net is discretized into multiple nodes and edges in our numerical approach, which is followed by an analytical formulation of the elastic energy and the associated Hessian matrix to realize the